Serum CK

Figure 1: Creatine Kinase levels between BL10 and MDX groups in serum samples. Mean and standard showing statistical significance (***) with a p-value < 0.001

Creatine kinase (CK) is a protein found in cardiac and skeletal muscle. Serum CK levels are routinely used as an indicator of muscle damage in dystrophic mice. Levels of this muscle protein are measured in the serum under the assumption that increased serum CK levels in the blood are representative of increased muscle damage, sarcolemma membrane fragility, and a poor disease phenotype.