Figure 2: Frequency in BL10 (n=15) versus MDX (n=15) male mice at 16 weeks. Mean with standard error showing a statistical significance (**) with p<0.01.
Plethysmography
Figure 2: Minute volume in BL10 (n=15) versus MDX (n=15) male mice at 16 weeks. Mean with standard error showing a statistical significance (***) with p<0.001.
Whole-body plethysmography is used to assess pulmonary function of mice by measuring flow and pressure changes that occur while breathing. Captured breathing parameters are: total volume, normalized tidal volume by bodyweight, inspiratory time, expiratory time, peak inspiratory flow, peak expiratory flow, relation time, minute volume and normalized minute volume by bodyweight, frequency, enhance pause, mid-expiratory flow and capture success rate.
http://www.treatnmd.eu/downloads/file/sops/dmd/MDX/DMD_M.2.2.002.pdf
