Grip Strength Measurements

Figure 2: Normalized forelimb grip strength for BL10 (n=12) versus MDX (n=12) male mice at 8 weeks. Mean with standard error showing statistical significance (***) with p< 0.001

Grip strength measurements are used to evaluate muscle force in vivo by taking advantage of a mouse’s natural tendency to grasp a horizontal metal grid. The grid is attached to a force transducer, and the force produced during the pull on the bar by the forelimbs can be repeatedly measured at desired intervals.